Alberta father searching for life-saving stem cell match for toddler

A Lac La Biche, Alta., man is desperately seeking a matching stem cell donor to save his sick son.

Jacob Marfo's two-year-old, Ezra, is currently in a Calgary hospital because of acute myelogenous leukemia,a cancer of the blood and bone marrow.

Ezra was born in June 2020 and diagnosed the next May.

"He is sick very very sick," Marfo told CBC Edmonton's Radio Active.

"Sometimes when you look at him, you can't even recognize he's the same boy that little fun boy who was running around."

Ezrahas gone through multiple rounds of chemotherapy. Hehas spent more time in hospitals than he has outside of them, according to his father.

"A stem cell transplant is part of the treatment package because this type of cancer destroys the stem cell in the bone marrow," Marfo said.

He said Ezra's chemotherapy and other treatments have not been successful and stressed the need for a stem cell donation from a perfect match.

Marfo is only a partial match for his sonand has already donated his own stem cells twice.

Now, as Ezra's condition worsens, he is searching for a better match.

Similar genetic background

Marfo and his family are from Ghana and more likely to find a matching donor among those who have a similar genetic background.

"Patients have better odds of matching within their own ethnicity when they do need to find that life-saving match," said Adrienne San Juan, community development manager at Canadian Blood Services.

Human leukocyte antigens proteins found in cells in the body are measured to rank matches. Most transplant doctors aim for a nine or 10 out of 10 match for stem cell transplants.

Ezra's family members in Canada have all been tested but no match was found.

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With restrictions on biological materials, hisfamily members in Ghana are unable to send their samples to Canada to be tested.

Marfo said he has completed forms giving hospitals in Ghana permission to test his family members. He hopes his brother, who lives in Ghana, is a match.

Marfo was at a stem cell drivein Toronto last weekendbecause it has a larger population of people of African and Caribbean descent.

Saving someone's life

Registering to be a stem cell donor is a quick and painless process.

"All we require is for you to fill out a quick health questionnaire and then just a quick swab of the inside of your mouth," San Juan said.

Anyone betweenthe ages of 17 and35 is eligible to register and will stay on the registry until the age of 60.

San Juan said it is rare you will actually get the call to donatebut registering will bring hope to Canadian patients in need of a match.

The procedure for donation is a one-day process similar to blood or plasma donation. Stem cells are separated from the blood, which is then injected back into the body.

"There's no loss to you because your stem cells regenerate after a few weeks," San Juan said.

Marfo is asking people to join the registry irrespective of background.

"My focus is my son Ezra," he said. "But at the hospital, there are a lot of other people who are waiting for a stem cell transplant."

San Juan said there are currently 1,386 patients in Canada waiting for a life-saving match.