Big Tobacco's divestment from Quebec's Medicago 'a step in the right direction' for its COVID vaccine

Tobacco company Philip Morris International has divested all of its shares from Medicago, a Canadian vaccine collaboratorwhose plant-based COVID-19 vaccine, Covifenz, was initially rejected by the World Health Organization over its ties with Big Tobacco.

In a statement on Thursday, Philip Morrisspokesperson David Fraser saidthe company decided to divest its stake in Medicago and that it's "the most appropriate way forward."

"We have long believed in the public health potential of Medicago's innovative approach for developing new plant-based vaccines and we hope this potential is realized for the benefit of global public health," Fraser said in an email.

Medicago, whose headquarters isin Quebec, is now 100 per centowned by Mitsubishi Tanabe Pharma. Before the decision, Philip Morris, whichproduces Marlboro cigarettes, owned 21 per centof the company's shares.

In an email to CBC News, the Quebec company said the divestment is "the most appropriate way forward." A spokesperson for Medicago saidthis ensures its "future growth and ability to achieve its mission," which is to "create and deliver effective responses to emerging global health challenges."

Covifenz can now reach international markets

In 2020, the federal government gave Medicago $173 million to develop itsvaccine, build a new production facility and purchase 76 million doses. In February, Health Canada approved Covifenz for adults 18 to 64 years old making it the first plant-based vaccine to be approved for use in Canada.

But in March, the World Health Organization (WHO) said it's not accepting Medicago's request for Covifenz's emergency use, due to the company's "linkage with the tobacco industry."

WHO saidthe decision was put on hold, which temporarily kept Covifenz out of COVAX, an international COVID-19 vaccine-sharing initiative.

Franois-Philippe Champagne, Canada's minister of innovation, science and industry, saidthe federal government has been working with Medicago and its shareholders to "find a solution that supports the growth of the company."

"This transaction is a step in the right direction, and we will continue to follow this matter very closely," Champagne said in an email.

Dr. Scott Halperin, director of the Canadian Centre for Vaccinology at Dalhousie University in Halifax, saidthe decision now allows Medicago to distribute its vaccine internationally if it reapplieswith WHO.

"It's important because it allows Medicago to play on the international stage ... so I think it could be very good news," Halperin said.

"One would have to hypothesize that if Medicago was no longer able to have any type of global vaccine market that they would be a horrible investment for anybody."

Public Services and Procurement Canada didn't answer CBC's questions on when the 76 million doses of Covifenz are expected to be delivered from Medicago.

In a statement, the department saidnegotiations between Ottawa and Medicago "are ongoing."

Decision applauded by tobacco critic

Les Hagen, executive director of Action on Smoking and Health, a charity advocating for tobacco control, reduction and prevention, saidhe's "relieved" that Canada is no longer collaborating with a multinational tobacco company.

"It's good news," he said. "Hopefully this vaccine can get another review by the World Health Organization."

Hagen criticized the government's decision to collaborate with Medicago in the first place, stating that public funds could havebeen better invested in otherCanadian companies that aren't backed by Big Tobacco, whichhe accuses of trying to "whitewash" itsimage.

"We felt that it was highly unethical. It's actually a contravention of a legally binding treaty: the Framework Convention onTobacco Control," he said.

The framework, which is managed by WHO, commits to protect public health policies "from the commercial and other vested interests of the tobacco industry." Canada signed it in 2005.

Earlier this year, aspokesperson for the Public Health Agency of Canada said the federal government "studied the matter of its investment in Medicago carefully" and believes it is still "compliant with its treaty obligations related to tobacco control" with WHO.

'We need that capacity in Canada'

Halperin of Dalhousie saidMedicago's vaccine is produced in the leaf of a plant that's a relative of tobaccoand that the plant itself acts as a "factory" for producing viral particles that are part of the vaccine.

"It's very novel technology," he said, adding that Covifenz is the first vaccine that uses this technology to fight COVID-19.

Canada lost the capabilityto produce its vaccines years ago due to the consolidation and buyoutof many companies, and the government has recognized that deficiency, Halperinsaid.

"That's going to take time to rebuild.... The Medicago story is just one aspect of it," he said, adding that it's critical to have domestic vaccine-supply ability because borders tend to close during emergencies.

"Despite what everybody says about global co-operation, borders still close and we need that capacity in Canada both for our own capability but also to contribute to the international scene."