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Health

Can't sleep in a new place? Your left brain might be why

The old adage about sleeping with one eye open in an unfamiliar place may not be too far off the mark. A small new study suggests that one half of the brain remains on high alert during the first night of sleep in a new space.

It's possible frequent travellers might adapt to first night effect over time

The old adage about sleeping with one eyeopen in an unfamiliar place may not be too far off the mark. A smallnew study suggests that one half of the brain remains on highalert during the first night of sleep in a new space.

Over the course of three experiments on 35 young, healthyvolunteers, researchers measured brain activity during twoconsecutive nights of sleep. They consistently found that partof the left side of the brain remained more active than theright side only on the first night, specifically during deepslow-wave sleep.

"When you sleep in a new place for the first time, a part ofone side of the brain seems to stay awake for surveillancepurposes, so you could wake up faster if necessary," said seniorstudy author Yuka Sasaki of Brown University.

While this may be bad news for business travellers whoregularly make brief overnight trips, it may not be astroublesome for people who go away for longer periods of time,Sasaki added by email.

"Frequent travel may lead to unrestful sleep," Sasaki said.

"But if you stay for a few days at the same place, your sleepmight catch up."

Differences in alertness

To see how being in a strange place impacts sleep, Sasakiand colleagues performed a series of lab tests on their
subjects.

When they stimulated the left hemisphere with irregularbeeping sounds in the right ear during deep sleep on the firstnight, that prompted significantly greater likelihood of wakingand faster action upon waking, than if sounds were played in theleft ear to stimulate the right hemisphere.

In other sleep phases during the first night, and with othertests, there wasn't any difference in alertness or activitybetween the two hemispheres of the brain, the researchers reportin the journal Current Biology, online April 21.

On the second night, there wasn't any difference inreactions to tests between the left and right hemispheres, evenduring deep sleep.

This suggests that there is a first-night-only effectspecifically in one hemisphere of the brain during deep sleep,the authors conclude. The way participants responded to thesleep lab tests points to the potential for the brain to be onhigh alert for danger during the first night in unfamiliarsurroundings.

Some birds have been found to literally sleep with one eyeopen and one side of the brain awake when they're in a dangeroussetting, and some marine mammals have similar abilities, theauthors note.

One limitation of the new study is its focus on healthyvolunteers, which means the results may not apply to people withinsomnia or other sleep disorders, the authors note.

While it's possible that the findings may explain poor sleepamong frequent travellers, the study wasn't designed to testwhether these "first night effects" continue to happen to peopleevery time they hit the road, said Patrick Finan, a psychiatryand behavioural health researcher at Johns Hopkins UniversitySchool of Medicine in Baltimore.

"It is possible, for example, that frequent travellers mightadapt to this first night effect over time," Finan, who wasn'tinvolved in the study, said by email.

"Any clinical implications would be speculative at themoment," Finan added. "However, the level of specificityprovided by these analyses could be an important first step inunderstanding who might be at risk for sleep disorders likeinsomnia, which is thought to be driven in many patients bychronic hypervigilance."