Bacteria with worrisome superbug genes found in U.S.
New Jersey researchers said they had identified perhaps the first strain of E. Coli bacteria in the United States with mobile genes that make it resistant to two types of antibiotics now considered last-line defenses against superbugs.
While patient treated successfully, researchers say bacterium has the potential to become powerful superbug
New Jersey researchers said on Mondaythey had identified perhaps the first strain of E. Coli bacteriain the United States with mobile genes that make it resistant totwo types of antibiotics now considered last-line defensesagainst superbugs.
Researchers said the strain of bacteria was found in a76-year-old man who was treated in 2014 for a complicatedurinary tract infection. Further analysis in 2016 showed thebacterium carried mcr-1, a gene that creates resistance to thelast-ditch antibiotic colistin. It was also shown to carryblaNDM-5, a gene that blocks effectiveness of carbapenems, whichare considered medicine's most reliable current antibiotics nowthat bacteria have found ways of outwitting other families ofantibiotics.
Results of the study were reported on Monday in mBio, anonline open-access journal of the American Society for
Microbiology.
Although the patient was treated successfully with otherantibiotics, researchers said the bacterium had the potential tospread and become a powerful superbug.
"The good news is that this did not cause a major outbreakof drug-resistant infection," said senior study author Barry
Kreiswirth, director of the Public Health Research InstituteTuberculosis Center at Rutgers University in Newark, New Jersey.
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